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It is the clinical context that determines whether the peptide’s mechanism is directed at the right problem, at the right intensity, for the right duration

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Necroptosis can also be materialized as a result of activation of the signaling pathways, due to DNA damage, which leads to the release of apoptosis-related factors from the mitochondrial intermembrane space, followed by the activation of the DNA damage–related enzyme poly(ADP-ribose) polymerase (PARP) [213]